According to Archives of Internal Medicine data on cytisine as a smoking cessation aid, the pharmacologically active dose of cytisine (assuming we credit the Eastern bloc research) is 3 – 9 mg/day.
Eric Marchewitz, (the founder and CEO of LG Sciences) has applied for a weight loss patent on cytisine, although there is no research to back up his claim. His patent application claims the effectiveness of cytisine at a daily dosage of between “0.2 to 1 mg.”
In large doses, cytisine can interfere with respiration and cause death. Some cytisine containing plants have been used as recreational drugs. Side effects of such use include headache, nausea, convulsions, vomiting, and the aforementioned respiratory failure (in higher doses).